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Hendrikx, T et al, inkl. Derdak, S und Bilban, M. Soluble TREM2 levels reflect the recruitment and expansion of TREM2 + macrophages that localize to fibrotic areas and limit NASH. J Hepatol 2022 Jun 15

Die CF Imaging und Genomics haben das 10x Genomics Visium Experiment durchgeführt.

 

Teresa Cruz-Bustos et al: The transcriptome from asexual to sexual in vitro development of Cystoisospora suis (Apicomplexa: Coccidia) Sci Rep. 2022 Apr 8

Die CF Genomics hat RNA-Sequenzierungen beigetragen und wird in den Methoden und im Acknowledgement genannt.

 

 

Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Heidemarie Rossiter  1 , Dragan Copic  2 , Martin Direder  2 , Florian Gruber  1 , Samuele Zoratto  3 , Martina Marchetti-Deschmann  3 , Christopher Kremslehner  1 , Michaela Sochorová  1 , Ionela-Mariana Nagelreiter  1   4 , Veronika Mlitz  1 , Maria Buchberger  1 , Barbara Lengauer  1 , Bahar Golabi  1 , Supawadee Sukseree  1 , Michael Mildner  1 , Leopold Eckhart  1 , Erwin Tschachler  Autophagy, 2021 Sep 7;1-15.Online ahead of print.
PMID: 34491140

APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ.
Nature, 2021 Sep; 597(7874):92-96.
PMID: 34433968

 

Breitenecker, K et al, inkl. Bilban, M. Down-regulation of A20 promotes immune escape of lung adenocarcinomas.  Sci Transl Med. 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.

 

Nasirzade, J et al, inkl. Mitulovic, G. Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling. Sci Rep. 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.


Wagner, G et al, inkl. Rauscher S, Gröger M, Derdak S und Bilban M. LMO3 reprograms visceral adipocyte metabolism during obesity. J Mol Med (Berl) 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.


Schieweck, R et al, inkl. Derdak, S und Bilban, M. Pumilio2 and Staufen2 selectively balance the synaptic proteome. Cell Rep 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.


Beltrán, E et al, inkl. Jeitler, M. Archeological neuroimmunology: resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis. Acta Neuropathol. 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.

 

Novoszel, P et al, inkl. Derdak, S. The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity. Cell Death and Differentiation 2021.


Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.

 

Mayer KA et al, inkl. Derdak, S and Bilban, M. The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells. FASEB Journal 2021

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalysen beigetragen.

 

Selective TiO2 Phosphopeptide Enrichment of Complex Samples in the Nanogram Range
Gábor Tóth, Fanni Bugyi, Simon Sugár, Goran Mitulović, Károly Vékey, Lilla Turiák and László Drahos
Separations 2020, 7(4), 74; https://doi.org/10.3390/separations7040074

Saliva proteomic patterns in patients with molar incisor hypomineralization
Bekes K, Mitulović G, Meißner N, Resch U, Gruber R
Scientific Reports volume 10, Article number: 7560 (2020), https://doi.org/10.1038/s41598-020-64614-z 

 

Adipose Stem Cell-Derived Extracellular Vesicles Induce Proliferation of Schwann Cells via Internalization
Maximilian Haertinger, Tamara Weiss, Anda Mann, Annette Tabi, Victoria Brandel, and Christine Radtke
Cells. 2020 Jan; 9(1): 163. Published online 2020 Jan 9
PMID: 31936601

Iamartino L et al, inkl. Derdak, S. Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor. Biochim Biophys Acta Mol Cell Res. 2020

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalyse beigetragen.

 

Gerner, MC et al, inkl. Derdak, S. The TGF-b/SOX4 axis and ROS-driven autophagy co-mediate CD39 expression in regulatory T-cells. FASEB J. 2020

Die Core Facilities Genomics hat zu dieser Publikation Microarray Dienstleistungen und Datenanalyse beigetragen.

 

Reisinger, SN et al, inkl. Bilban, M und Derdak, S. Lmo3 deficiency in the mouse is associated with alterations in mood-related behaviors and a depression-biased amygdala transcriptome. Psychoneuroendocrinology. 2020

Die Core Facilities Genomics hat zu dieser Publikation Illumina RNA-Sequenzier-Dienstleistungen und Datenanalyse beigetragen.

 

Pammer, J et al, inkl. Bilban, M. PIWIL-2 and piRNAs are regularly expressed in epithelia of the skin and their expression is related to differentiation. Arch Dermatol Res. 2020

Die Core Facilities Genomics hat zu dieser Publikation Illumina smallRNA-Sequenzier-Dienstleistungen beigetragen.

 

Pillar array columns for peptide separations in nanoscale reversed-phase chromatography.
Tóth G, Panić-Janković T, Mitulović G. 
J Chromatogr A. 2019 Oct 11;1603:426-432. doi: 10.1016/j.chroma.2019.06.067. Epub 2019 Jul 4. PubMed PMID: 31301798.

Human chorionic gonadotrophin pharmaceutical formulations of urinary origin display high levels of contaminant proteins-A label-free quantitation proteomics study.
Panić-Janković T, Mitulović G. 
Electrophoresis. 2019 Jun;40(11):1622-1629. doi: 10.1002/elps.201900087. Epub 2019 Mar 25. PubMed PMID: 30883802; PubMed Central PMCID: PMC6593423.

Cell death induced autophagy contributes to terminal differentiation of skin and skin appendages.
Koenig U, Robenek H, Barresi C, Brandstetter M, Resch GP, Gröger M, Pap T, Hartmann C.
Autophagy. 2019 Aug 4:1-14. doi: 10.1080/15548627.2019.1646552. [Epub ahead of print]
PMID: 31379249

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.
Laszlo V, Valko Z, Ozsvar J, Kovacs I, Garay T, Hoda MA, Klikovits T, Stockhammer P, Aigner C, Gröger M, Klepetko W, Berger W, Grusch M, Tovari J, Waizenegger IC, Dome B, Hegedus B.
J Mol Med (Berl). 2019 Feb; 97(2):231-242.
PMID: 30539198

 

Mohrherr, J et al, inkl. Bilban, M. JAK–STAT inhibition impairs K‐RAS‐driven lung adenocarcinoma progression. Int J Cancer. 2019

 

Acid bone lysate activates TGFβ signalling in human oral fibroblasts.
Strauss FJ, Stähli A, Beer L, Mitulović G, Gilmozzi V, Haspel N, Schwab G, Gruber R.
Sci Rep. 2018 Oct 30;8(1):16065. doi: 10.1038/s41598-018-34418-3.
https://www.ncbi.nlm.nih.gov/pubmed/30375456

Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances.
Ohradanova-Repic A, Machacek C, Charvet C, Lager F, Le Roux D, Platzer R, Leksa V, Mitulovic G, Burkard TR, Zlabinger GJ, Fischer MB, Feuillet V, Renault G, Blüml S, Benko M, Suchanek M, Huppa JB, Matsuyama T, Cavaco-Paulo A, Bismuth G, Stockinger H. 
Front Immunol. 2018 Apr 27;9:852. doi: 10.3389/fimmu.2018.00852.
https://www.ncbi.nlm.nih.gov/pubmed/29780382

Serum proteomic pattern in female stress urinary incontinence.
Koch M, Umek W, Hanzal E, Mohr T, Seyfert S, Koelbl H, Mitulović G.
Electrophoresis. 2018 Jan 23. doi: 10.1002/elps.201700423. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29359342

Impact of combined treatment with nimesulide and cisplatin on oral carcinoma cells.
Barac A, Mitulovic G, Hallström S, Zehetmayer S, Grasl MC, Erovic BM.
https://doi.org/10.2147/OTT.S131106
https://www.ncbi.nlm.nih.gov/pubmed/28790852

Serum proteomic pattern in female stress urinary incontinence.
Koch M, Umek W, Hanzal E, Mohr T, Seyfert S, Koelbl H, Mitulović G.
Electrophoresis. 2018 Jan 23. doi: 10.1002/elps.201700423. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29359342

Neutrophil-Mediated Proteolysis of Thrombospondin-1 Promotes Platelet Adhesion and String Formation.
Seif K, Alidzanovic L, Tischler B, Ibrahim N, Zagrapan B, Rauscher S, Salzmann M, Hell L, Mauracher LM, Budde U, Schmid JA, Jilma B, Pabinger I, Assinger A, Starlinger P, Brostjan C.
Thromb Haemost. 2018 Dec;118(12):2074-2085. doi: 10.1055/s-0038-1675229. Epub 2018 Nov 12.
PMID: 30419595


Inactivation of autophagy leads to changes in sebaceous gland morphology and function.
Rossiter H, Stübiger G, Gröger M, König U, Gruber F, Sukseree S, Mlitz V, Buchberger M, Oskolkova O, Bochkov V, Eckhart L, Tschachler E.
Exp Dermatol. 2018 Oct; 27(10):1142-1151.
PMID: 30033522

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.
Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B.
Clin Cancer Res. 2018 Aug 1; 24(15):3729-3740.
PMID: 29724868

CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis.
Soler-Cardona A, Forsthuber A, Lipp K, Ebersberger S, Heinz M, Schossleitner K, Buchberger E, Gröger M, Petzelbauer P, Hoeller C, Wagner E, Loewe R.
J Invest Dermatol. 2018 Feb 20. pii: S0022-202X(18)30125-8 [Epub ahead of print]
PMID:29474942

 

Immobilized monolithic enzymatic reactors and its application on analysis of In-Vitro Fertilization media samples (2017)
Wei-Qiang Chen, Philipp Obermayr, Urh Černigoj, Jana Vidič, Tanja Panić-Janković, Goran Mitulović

ELECTROPHORESIS
DOI: 10.1002/elps.201700197
http://onlinelibrary.wiley.com/doi/10.1002/elps.201700197/full

 

Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments.
Miller A, Nagy C, Knapp B, Laengle J, Ponweiser E, Groeger M, Starkl P, Bergmann M, Wagner O, Haschemi A.
Cell Metab. 2017 Nov 7;26(5):788-800. Epub 2017 Sep 7.
PMID:28889950

Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo.
Hock K, Laengle J, Kuznetsova I, Egorov A, Hegedus B, Dome B, Wekerle T, Sachet M, Bergmann M.
Surgery. 2017 Mar;161(3):735-746. doi: 10.1016/j.surg.2016.08.045. Epub 2016 Oct 21.
PMID:27776794

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.
Stojkovic S, Thulin Å, Hell L, Thaler B, Rauscher S, Baumgartner J, Gröger M, Ay C, Demyanets S, Neumayer C, Huk I, Spittler A, Huber K, Wojta J, Siegbahn A, Åberg M.
Thromb Haemost. 2017 May 11. doi: 10.1160/TH16-10-0784. [Epub ahead of print]
PMID: 28492698 [PubMed - as supplied by publisher]

A Rapid Automated Protocol for Muscle Fiber Population Analysis in Rat Muscle Cross Sections Using Myosin Heavy Chain Immunohistochemistry.
Bergmeister KD, Gröger M, Aman M, Willensdorfer A, Manzano-Szalai K, Salminger S, Aszmann OC.
J Vis Exp. 2017 Mar 28;(121). doi: 10.3791/55441.
PMID: 28448058 [PubMed - in process]

Does Extracellular DNA Production Vary in Staphylococcal Biofilms Isolated From Infected Implants versus Controls?
Zatorska B, Groger M, Moser D, Diab-Elschahawi M, Lusignani LS, Presterl E.
Clin Orthop Relat Res. 2017 Feb 13. doi: 10.1007/s11999-017-5266-0.
[Epub ahead of print]
PMID: 28194715 [PubMed - as supplied by publisher]

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.
Wagner G, Lindroos-Christensen J, Einwallner E, Husa J, Zapf TC, Lipp K, Rauscher S, Gröger M, Spittler A, Loewe R, Gruber F, Duvigneau JC, Mohr T, Sutterlüty-Fall H, Klinglmüller F, Prager G, Huppertz B, Yun J, Wagner O, Esterbauer H, Bilban M.
Sci Rep. 2017 Jan 19;7:40881. doi: 10.1038/srep40881.
PMID: 28102348 [PubMed - in process]Free PMC Article

Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
Buchberger E, Payrhuber D, El Harchi M, Zagrapan B, Scheuba K, Zommer A, Bugyik E, Dome B, Kral JB, Schrottmaier WC, Schabbauer G, Petzelbauer P, Gröger M, Bilban M, Brostjan C.
Oncotarget. 2017 Jan 3;8(1):552-564. doi: 10.18632/oncotarget.13477.
PMID: 27880939 [PubMed - in process]Free PMC Article

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin.  Tripisciano C, Weiss R, Eichhorn T, Spittler A, Heuser T, Fischer MB, Weber V. Sci Rep. 2017 Jul 26;7(1):6522. doi: 10.1038/s41598-017-03262-PMID: 28747771 Free PMC Article

Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid.  Herzog R, Kuster L, Becker J, Gluexam T, Pils D, Spittler A, Bhasin MK, Alper SL, Vychytil A, Aufricht C, Kratochwill K. Sci Rep. 2017 Jul 24;7(1):6229. doi: 10.1038/s41598-017-05872-2. PMID: 28740213 Free PMC Article

Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1. Edlinger L, Berger-Becvar A, Menzl I, Hoermann G, Greiner G, Grundschober E, Bago-Horvath Z, Al-Zoughbi W, Hoefler G, Brostjan C, Gille L, Moriggl R, Spittler A, Sexl V, Hoelbl-Kovacic A. Br J Haematol. 2017 Oct;179(2):229-241. doi: 10.1111/bjh.14833. Epub 2017 Jul 14. PMID: 28707321

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets. Stojkovic S, Thulin Å, Hell L, Thaler B, Rauscher S, Baumgartner J, Gröger M, Ay C, Demyanets S, Neumayer C, Huk I, Spittler A, Huber K, Wojta J, Siegbahn A, Åberg M.
Thromb Haemost. 2017 Jun 28;117(7):1379-1390. doi: 10.1160/TH16-10-0784. Epub 2017 May 11.
PMID: 28492698

Bedside Immune Monitoring: An Automated Immunoassay Platform for Quantification of Blood Biomarkers in Patient Serum within 20 Minutes. Zirath H, Schnetz G, Glatz A, Spittler A, Redl H, Peham JR. Anal Chem. 2017 May 2;89(9):4817-4823. doi: 10.1021/acs.analchem.6b03624. Epub 2017 Apr 19. PMID: 28382820

Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro.
Schüller SS, Wisgrill L, Herndl E, Spittler A, Förster-Waldl E, Sadeghi K, Kramer BW, Berger A.
Pediatr Res. 2017 Aug;82(2):215-225. doi: 10.1038/pr.2017.41. Epub 2017 May 24. PMID: 28288151

Potential role of platelet-leukocyte aggregation in trauma-induced coagulopathy: Ex vivo findings.
Zipperle J, Altenburger K, Ponschab M, Schlimp CJ, Spittler A, Bahrami S, Redl H, Schöchl H.
J Trauma Acute Care Surg. 2017 May;82(5):921-926. doi: 10.1097/TA.0000000000001410.
PMID: 28257393

Procoagulant extracellular vesicles in amniotic fluid. Hell L, Wisgrill L, Ay C, Spittler A, Schwameis M, Jilma B, Pabinger I, Altevogt P, Thaler J. Transl Res. 2017 Jun;184:12-20.e1. doi: 10.1016/j.trsl.2017.01.003. Epub 2017 Feb 4. PMID: 28236427

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2. Wagner G, Lindroos-Christensen J, Einwallner E, Husa J, Zapf TC, Lipp K, Rauscher S, Gröger M, Spittler A, Loewe R, Gruber F, Duvigneau JC, Mohr T, Sutterlüty-Fall H, Klinglmüller F, Prager G, Huppertz B, Yun J, Wagner O, Esterbauer H, Bilban M. Sci Rep. 2017 Jan 19;7:40881. doi: 10.1038/srep40881. PMID: 28102348 Free PMC Article

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity. Li J, Casteels T, Frogne T, Ingvorsen C, Honoré C, Courtney M, Huber KV, Schmitner N, Kimmel RA, Romanov RA, Sturtzel C, Lardeau CH, Klughammer J, Farlik M, Sdelci S, Vieira A, Avolio F, Briand F, Baburin I, Májek P, Pauler FM, Penz T, Stukalov A, Gridling M, Parapatics K, Barbieux C, Berishvili E, Spittler A, Colinge J, Bennett KL, Hering S, Sulpice T, Bock C, Distel M, Harkany T, Meyer D, Superti-Furga G, Collombat P, Hecksher-Sørensen J, Kubicek S. Cell. 2017 Jan 12;168(1-2):86-100.e15. doi: 10.1016/j.cell.2016.11.010. Epub 2016 Dec 1. PMID: 27916275 Free PMC Article

 

Titanium dioxide nanoparticle coating of polymethacrylate-based chromatographic monoliths for phosphopetides enrichment.
Černigoj U, Gašperšič J, Fichtenbaum A, Lendero Krajnc N, Vidič J, Mitulović G, Štrancar A. 
Anal Chim Acta (2016 Oct 26);942:146-154. doi: 10.1016/j.aca.2016.08.044.
PubMed PMID: 27720118.

Hyperoxia Induces Inflammation and Cytotoxicity in Human Adult Cardiac Myocytes.
Hafner C, Wu J, Tiboldi A, Hess M, Mitulovic G, Kaun C, Krychtiuk KA, Wojta J, Ullrich R, Tretter EV, Markstaller K, Klein KU.
Shock (2016 Sep 19).
[Epub ahead of print] PubMed PMID: 27648689.

Folate Receptor β Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen.
Machacek C, Supper V, Leksa V, Mitulovic G, Spittler A, Drbal K, Suchanek M, Ohradanova-Repic A, Stockinger H.
J Immunol. (2016 Sep 15);197(6):2229-38. doi: 10.4049/jimmunol.1501878. Epub 2016 Aug 17.
PubMed PMID: 27534550.

Maternal Embryonic Leucine Zipper Kinase (MELK): a Novel Marker of Poor Prognosis and Attractive Drug Target in High-Risk Patients with Multiple Myeloma.
Bolomsky, A., Schlangen, K., Köhler, A., Mitulovic, G., Schreiner, W., Zojer, N., &Ludwig, H. (2015).
Blood, 126(23), 1823.Accessed September 21, 2016. Retrieved from http://www.bloodjournal.org/content/126/23/1823.

Direct injection of HILIC fractions on the reversed phase trap column improves protein identification rates for salivary proteins.
Fichtenbaum A, Schmid R, Mitulović G.
Electrophoresis (2016 Jul 27). doi: 10.1002/elps.201600222.
PMID: http://www.ncbi.nlm.nih.gov/pubmed/27461483

Urinary proteomic pattern in female stress urinary incontinence: a pilot study
Marianne Koch, Goran Mitulovic, Engelbert Hanzal, Wolfgang Umek, Sonja Seyfert, Thomas Mohr, Heinz Koelbl, Rosa Maria Laterza
International Urogynecology Journal (May 2016)
PMID:27193112
http://link.springer.com/article/10.1007%2Fs00192-016-3033-5

Depletion of human serum albumin in embryo culture media for in vitro fertilization using monolithic columns with immobilized antibodies
Irina A. Tarasova, Anna A. Lobas, Urh Cernigoj, Elizaveta M. Solovyeva, Barbara Mahlberg, Mark V. Ivanov, Tanja Panic-Jankovic, Zoltan Nagy, Marina L. Pridatchenko, Andras Pungor, Blaz Nemec, Urska Vidic, Jernej Gaspersic, Nika Lendero Krajnc, Jana Vidic, Mikhail V. Gorshkov, Goran Mitulovic
Electrophoresis 2016 April 28 DOI: 10.1002/elps.201500489
http://onlinelibrary.wiley.com/doi/10.1002/elps.201500489/full

Low-Temperature Mobile Phase for Peptide Trapping at Elevated Separation Temperature Prior to Nano RP-HPLC-MS/MS
Matthias Schöbinger, Oskar-James Klein and Goran Mitulović
Chromatography 2016, 3(1), 6; doi:10.3390/chromatography3010006
Communication

Association of CD147 and Calcium Exporter PMCA4 Uncouples IL-2 Expression from Early TCR Signaling.
Supper V, Schiller HB, Paster W, Forster F, Boulègue C, Mitulovic G, Leksa V, Ohradanova-Repic A, Machacek C, Schatzlmaier P, Zlabinger GJ, Stockinger H.
J Immunol. 2016 Feb 1;196(3):1387-99. doi: 10.4049/jimmunol.1501889. Epub 2016 Jan 4.
PMID: 26729804

KINFix - A formalin-free non-commercial fixative optimized for histological, immunohistochemical and molecular analyses of neurosurgical tissue specimens.
Stefanits H, Bienkowski M, Galanski M, Mitulovic G, Ströbl T, Gelpi E, Ribalta T,
Broholm H, Hartmann C, Kros JM, Preusser M, Hainfellner JA.
Clin Neuropathol. 2016 Jan-Feb;35(1):3-12. doi: 10.5414/NP300907. No abstract available.
PMID:26521938

 

Polystyrene-Divinylbenzene-Based Adsorbents Reduce Endothelial Activation and Monocyte Adhesion Under Septic Conditions in a Pore Size-Dependent Manner.
Eichhorn T, Rauscher S, Hammer C, Gröger M, Fischer MB, Weber V.
Inflammation. 2016 Oct;39(5):1737-46. doi: 10.1007/s10753-016-0408-1.
PMID: 27503310 [PubMed - indexed for MEDLINE]Free PMC Article

 Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography.
Fialová S, Augustin M, Glösmann M, Himmel T, Rauscher S, Gröger M, Pircher M, Hitzenberger CK, Baumann B.
Biomed Opt Express. 2016 Mar 24;7(4):1479-95. doi: 10.1364/BOE.7.001479. eCollection 2016 Apr 1.
PMID: 27446670 [PubMed]Free PMC Article

Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells.
Montanari E, Stojkovic S, Kaun C, Lemberger CE, de Martin R, Rauscher S, Gröger M, Maurer G, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.
Thromb Haemost. 2016 Aug 1;116(2):317-27. doi: 10.1160/TH15-12-0917. Epub 2016 May 12.
PMID: 27173404 [PubMed - in process]

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation.
Stojkovic S, Kaun C, Basilio J, Rauscher S, Hell L, Krychtiuk KA, Bonstingl C, de Martin R, Gröger M, Ay C, Holnthoner W, Eppel W, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.
Sci Rep. 2016 May 4;6:25171. doi: 10.1038/srep25171.
PMID: 27142573 [PubMed - in process]Free PMC Article

Evidence That Cingulin Regulates Endothelial Barrier Function In Vitro and In Vivo.
Schossleitner K, Rauscher S, Gröger M, Friedl HP, Finsterwalder R, Habertheuer A, Sibilia M, Brostjan C, Födinger D, Citi S, Petzelbauer P.
Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):647-54. Epub 2016 Jan 28. PMID: 26821949

Neutrophil Gelatinase-Associated Lipocalin (NGAL) is Associated with Symptomatic Carotid Atherosclerosis and Drives Pro-inflammatory State In Vitro.
Eilenberg W, Stojkovic S, Piechota-Polanczyk A, Kaun C, Rauscher S, Gröger M, Klinger M, Wojta J, Neumayer C, Huk I, Demyanets S.
Eur J Vasc Endovasc Surg. 2016 Feb 29. [Epub ahead of print] PMID:26947538

Automated muscle fiber type population analysis with ImageJ of whole rat muscles using rapid myosin heavy chain immunohistochemistry.
Bergmeister KD, Gröger M, Aman M, Willensdorfer A, Manzano-Szalai K, Salminger S, Aszmann OC.
Muscle Nerve. 2016 Jan 20.[Epub ahead of print] PMID:26788932

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.
Sadeghi K, Wisgrill L, Wessely I, Diesner SC, Schüller S, Dürr C, Heinle A, Sachet M, Pollak A, Förster-Waldl E, Spittler A. PLoS One. 2016 Oct 3;11(10):e0162667. doi: 10.1371/journal.pone.0162667. eCollection 2016. PMID: 27695085 Free PMC Article

Folate receptor beta regulates integrin CD11b/CD18 adhesion of a macrophage subset to collagen. (2016) Machacek C, Supper V, Leksa V, Mitulovic G, Spittler A, Drbal K, Suchanek M, Ohradanova-Repic A and H. Stockinger. Journal of Immunology, Aug 17. pii: 1501878. PMID: 27534550

Characterization of Extracellular Vesicles in Whole Blood: Influence of Pre-Analytical Parameters and Visualization of Vesicle-Cell Interactions Using Imaging Flow Cytometry. Fendl B., Weiss R., Fischer MB., Spittler A. and V. Weber. (2016) Biochemical and Biophysical Research Communications (BBRC), Jul 19. pii: S0006-291X(16)31195-0. doi: 10.1016/j.bbrc.2016.07.073 PMID: 27444383

Peripheral Blood Microvesicles Secretion is Influenced by Storage Time, Temperature and Anticoagulants. Wisgrill L., Lamm C., Hartmann J., Preißing F., Dragosits K., Bee A., Hell L., Thaler J., Ay C., Pabinger I., Berger A. and A. Spittler. (2016) Cytometry Part A, 89:663-72 PMID: 27442840

Effect of hemoadsorption during cardiopulmonary bypass surgery – a blinded, randomized, controlled pilot study using a novel adsorbent. Bernardi M.H., Rinoesl H., Dragosits K., Ristl R., Hoffelner F., Opfermann P., Lamm C., Preißing F., Wiedemann D., Hiesmayr M.J. and A. Spittler. (2016) Crit Care, 20:96 PMID: 27059056

Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response. Schauer D., Starlinger P., Alidzanovic L., Zajc P., Maier T., Feldman A., Padickakudy R., Buchberger E., Elleder V., Spittler A., Stift J., Pop L., Gruenberger B., Gruenberger T. and C. Brostjan. (2016) OncoImmunology, Mar 22;5(6):e1160185. PMID: 27471631

Reduced TNFα Response in Preterm Neonates is Associated with Impaired Non-Classical Monocyte Function. Wisgrill L., Groschopf A., Herndl E., Sadeghi K., Spittler A., Berger A., and E. Förster-Waldl. (2016) J Leukocyte Biology, pii: jlb.4A0116-001RR   PMID: 26965638

The TLR-specific Adjuvants R-848 and CpG-B Endorse the Immunological Reaction of Neonatal Antigen Presenting Cells. Schüller S., Wisgrill L., Sadeghi K., Gindl E., Helnmer H., Husslein P., Berger A., Spittler A. and E. Förster-Waldl. (2016) Ped Research, doi: 10.1038/pr.2016.71 PMID: 27057737

A compact and integrated immunoassay with on-chip dispensing and magnetic particle handling. Zirath H., Peham J.R., Schnetz G., Coll A., Brandhoff L., Spittler A., Vellekoop M.J. and  H. Redl. (2016) Biomedical Microdevices, 18:16 PMID: 26842948

Single-cell transcriptomics reveals unique features of human pancreatic islet cell subtypes. Kubicek S., Li J., Klughammer J, Farlik M., Penz T., Spittler A., Barbieux C., Berishvili E. and C. Bock. (2016) EMBO, 17:178-87 PMID: 26691212

 

New HPLC Techniques for Proteomics Analysis: A Short Overview of Latest Developments
Goran Mitulovic, Mechtler, K.
Journal of Liquid Chromatography & Related Technologies
Volume 38, Issue 3, 2015
DOI: 10.1080/10826076.2014.941266
PMID: 17124183

Melatonin: Free Radicals and Metabolites Resulting by Emission and Consumption of Solvated Electrons (eaq-): Reaction Mechanisms.
Kneidinger H, Mitulovic G, Hartmann J, Quint RM, Getoff N.
In Vivo. 2015 Sep-Oct;29(5):605-9.
PMID:26359421

Proteome analysis of testis from infertile protein C inhibitor-deficient mice reveals novel changes in serpin processing and prostaglandin metabolism.
Yang H, Wahlmüller FC, Uhrin P, Baumgartner R, Mitulovic G, Sarg B, Geiger M, Zellner M.
Electrophoresis. 2015 Aug 31. doi: 10.1002/elps.201500218. [Epub ahead of print]
PMID:26332751[uid]

Differential Potential of Pharmacological PARP Inhibitors for Inhibiting Cell Proliferation and Inducing Apoptosis in Human Breast Cancer Cells.
Wesierska-Gadek J, Mauritz M, Mitulovic G, Cupo M.
J Cell Biochem. 2015 Dec;116(12):2824-39. doi: 10.1002/jcb.25229.
PMID:25981734
 

Spectral degree of polarization uniformity for polarization-sensitive OCT.Baumann B, Zotter S, Pircher M, Götzinger E, Rauscher S, Glösmann M, Lammer J, Schmidt-Erfurth U, Gröger M, Hitzenberger CK.
J Mod Opt. 2015;62(21):1758-1763 PMID:2668982

Melanin Pigmentation in Rat Eyes: In Vivo Imaging by Polarization-Sensitive Optical Coherence Tomography and Comparison to Histology.
Baumann B, Schirmer J, Rauscher S, Fialová S, Glösmann M, Augustin M, Pircher M, Gröger M, Hitzenberger CK.
JInvest Ophthalmol Vis Sci. 2015. Nov 1;56(12):7462-72. PMID:2659606

Mouse hippocampal GABAB1 but not GABAB2 subunit-containing receptor complex levels are paralleling retrieval in the multiple-T-maze.
Falsafi SK, Ghafari M, Miklósi AG, Engidawork E, Gröger M, Höger H, Lubec G.
Front Behav Neurosci. 2015. Oct 19;9:276. eCollection 2015. PMID:26539091

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines.
Mahmmoud RR, Sase S, Aher YD, Sase A, Gröger M, Mokhtar M, Höger H, Lubec G.
PLoS One. 2015. Oct 15;10(10):e0139739. eCollection 2015. PMID:26469788

Molecular and biochemical characterization of Entamoeba histolytica fructokinase.
Matt J, Duchêne M..
Parasitol Res. 2015. May;114(5):1939-47. Epub 2015 Feb 21. PMID:25700717

Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze.
Shanmugasundaram B, Sase A, Miklosi AG, Sialana FJ, Subramaniyan S, Aher YD, Gröger M, Höger H, Bennett KL, Lubec G.
Behav Brain Res. . Epub 2015 Apr 28. [Epub ahead of print] PMID:25930220

Individual phases of contextual fear conditioning differentially modulate dorsal and ventral hippocampal GluA1-3, GluN1-containing receptor complexes and subunits.
Sase S, Sase A, Sialana FJ Jr, Gröger M, Bennett KL, Stork O, Lubec G, Li L.
Hippocampus..2015 Apr 25. [Epub ahead of print] PMID:25914080

Drebrin depletion alters neurotransmitter-receptor levels in protein-complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus.
Jung G, Kim EJ, Cicvaric A, Sase S, Gröger M, Höger H, Sialana FJ, Berger J, Monje FJ, Lubec G.
J Neurochem. 2015 Apr 11. [Epub ahead of print] PMID:25865831

Hippocampal receptor complexes paralleling LTP reinforcement in the spatial memory holeboard test in the rat.
Subramaniyan S, Hajali V, Scherf T, Sase SJ, Sialana FJ, Gröger M, Bennett KL, Pollak A, Li L, Korz V, Lubec G.
Behav Brain Res. 2015 Apr 15; 283:162-74. Epub 2015 Jan 30. PMID: 25639541

Autophagy facilitates secretion and protects against degeneration of the Harderian gland.
Koenig U, Fobker M, Lengauer B, Brandstetter M, Resch GP, Gröger M, Plenz G, Pammer J, Barresi C, Hartmann C, Rossiter H.
Autophagy. 2015 Feb;11(2):298-313. PMID:25484081

Release and cellular origin of extracellular vesicles during circulation of whole blood over adsorbent polymers for lipid apheresis. Weiss R., Eichhorn T., Spittler A., Micusik M., Fischer M. and V. Weber. (2015) Journal of Biomedical Materials Research, Part B – Applied Biomaterials, doi: 10.1002/jbm.b.33588. PMID: 26671881

EVI1 promotes tumor growth via transcriptional repression of MS4A3.
Heller G., Rommer A., Steinleitner K., Etzler J., Hackl H., Heffeter P., Tomasich E., Filipits M., Steinmetz B., Topakian T., Klingenbrunner S., Ziegler B., Spittler A., Zöchbauer-Müller S., Berger W. and R. Wieser.
J Hematol Oncol 2015, 21;8:28.
PMID: 25886616

Multi-Purpose Ultrasonic Streaming Mixer for Integrated Magnetic Beads ELISAs.
Brandhoff L., Zirath H., Salas M., Haller A., Peham, J., Wiesinger-Mayr H., Spittler A., Schnetz G., Lang W. and M. Vellekoop.
J Micromech Microeng 2015, JMM-101394.R3

 

 

 

A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype.
Veitinger M, Oehler R, Umlauf E, Baumgartner R, Schmidt G, Gerner C, Babeluk R, Attems J, Mitulovic G, Rappold E, Lamont J, Zellner M.
Acta Neuropathol. 2014 Nov;128(5):665-77. doi: 10.1007/s00401-014-1341-8. Epub 2014 Sep 24.
PMID:25248508 | PMCID:PMC4201753

Corticosterone metabolites originating as a consequence of solvated electron (e(-)aq) emission.
Brenn E, Mitulovic G, Quint RM, Getoff N.
In Vivo. 2014 Sep-Oct;28(5):879-84.
PMID:25189903[uid]

Empirical multidimensional space for scoring peptide spectrum matches in shotgun proteomics.
Ivanov MV, Levitsky LI, Lobas AA, Panic T, Laskay ÜA, Mitulovic G, Schmid R, Pridatchenko ML, Tsybin YO, Gorshkov MV.
J Proteome Res. 2014 Apr 4;13(4):1911-20. doi: 10.1021/pr401026y. Epub 2014 Mar 13.
PMID:24571493

Peripapillary rat sclera investigated in vivo with polarization-sensitive optical coherence tomography.
Baumann B, Rauscher S, Glösmann M, Götzinger E, Pircher M, Fialová S, Gröger M, Hitzenberger CK.
Invest Ophthalmol Vis Sci. 2014 Oct 28;55(11):7686-96. PMID:25352116

Monocytes with angiogenic potential are selectively induced by liver resection and accumulate near the site of liver regeneration.
Schauer D, Starlinger P, Zajc P, Alidzanovic L, Maier T, Buchberger E, Pop L, Gruenberger B, Gruenberger T, Brostjan C.
BMC Immunol. 2014. Oct 30;15:50. PMID:25359527

Dynamic O-Linked N-Acetylglucosamine Modification of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids.
Herzog R, Bender TO, Vychytil A, Bialas K, Aufricht C, Kratochwill K.
J Am Soc Nephrol. 2014 May 22. [Epub ahead of print] PMID:24854264

Interleukin-33 induces urokinase in human endothelial cells – possible impact on angiogenesis.
Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S.
J Thromb Haemost. 2014 Jun;12(6):948-57. PMID:24702774

Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro.
Krychtiuk KA, Watzke L, Kaun C, Buchberger E, Hofer-Warbinek R, Demyanets S, Pisoni J, Kastl SP, Rauscher S, Gröger M, Aliabadi A, Zuckermann A, Maurer G, de Martin R, Huber K, Wojta J, Speidl WS.
Thromb Haemost. 2014 Oct 2;113(1). PMID: 25273157

Protein kinases paralleling late-phase LTP formation in dorsal hippocampus in the rat.
Li L, Jia W, Sase S, Gröger M, Pollak A, Korz V, Lubec G.
Neurochem Int. 2014 Jun 6.S0197-0186(14)00136-3. PMID:24911953

Interleukin-33 induces urokinase in human endothelial cells-possible impact on angiogenesis.
Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S.
J Thromb Haemost. 2014 Jun;12(6):948-57. PMID:24702774

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells.
Rohringer S., Holnthoner W., Hackl M., Skalicky S., Proell J., Schweighofer B. Groeger M., Spittler A., Grillari J. and H. Redl.
Plos ONE 2014, 11;9(12):e114806. doi: 10.1371/journal.pone.0114806.
PMID: 25502694

Vortex enhancement in microfluidic flows for on-chip sample preparation.
Haller A., Spittler A., Brandhoff L., Zirath H., Puchberger-Enengl D., Keplinger F. and M.J. Vellekoop,
Miromachines 2014, 6,2;13 S.

Serum-dependent processing of late apoptotic cells for enhanced efferocytosis.
Liang Y.Y., Arnold T., Michlmayr A., Rainprecht D., Perticevic B., Spittler A. and R. Oehler.
Cell Death and Disease 2014, 29:e1264. PMID: 24874736

Thrombocyte adhesion and release of extracellular microvesicles correlate with surface morphology of adsorbent polymers for lipid apheresis.
Weiss R., Spittler A., Schmitz G., Fischer M.B. and V. Weber.
Biomacromolecules 2014, 15:2648-55. PMID: 24844344

Hematopoietic stem cells in neonates: any difference between very preterm and term neonates?
Wisgrill L., Schüller S., Bammer M., Berger A., Pollak A., Radke T.F., Kögler G., Spittler A., Helmer H., Husslein P. and L. Gortner.
PLoS ONE 2014, 9(9):e106717.

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid.
Steinmetz B., Hackl H., Slabáková E., Schwarzinger I., Smejová M., Spittler A., Arbesu I., Shehata M., Soucĕk K. and R. Wieser.
Cell Cycle 2014, 13:18, 2931-43. PMID: 25486480

HIF-1alpha Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells.
Marhold M., Tomasich E., El-Gazzar A., Heller G., Spittler A., Horvat R., Krainer M. and P. Horak.
Molecular Cancer Research 2014, Oct 27. pii: molcanres.0153.2014. PMID: 25349289

 

 

 

 

Identification and validation of platelet low biological variation proteins, superior to GAPDH, actin and tubulin, as tools in clinical proteomics.
Baumgartner R, Umlauf E, Veitinger M, Guterres S, Rappold E, Babeluk R, Mitulovic G, Oehler R, Zellner M.
J Proteomics. 2013 Dec 6;94:540-51. doi: 10.1016/j.jprot.2013.10.015. Epub 2013 Oct 25.
PMID:24284060

Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes.
Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch-Klupp I, Bilban M, Brostjan C.
PLoS One. 2013 Oct 11;8(10):e76845. PMID:24146931 

Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. 
Madlener S, Ströbel T, Vose S, Saydam O, Price BD, Demple B, Saydam N.
Proc Natl Acad Sci U S A. 2013 Oct 14. [Epub ahead of print] PMID:23823477

GSK-3β inhibition protects mesothelial cells during experimental peritoneal dialysis through upregulation of the heat shock response.
Rusai K, Herzog R, Kuster L, Kratochwill K, Aufricht C.
Cell Stress Chaperones. 2013 Sep;18(5):569-79. PMID:23494401

Human but not mouse adipogenesis is critically dependent on LMO3. 
Lindroos J, Husa J, Mitterer G, Haschemi A, Rauscher S, Haas R, Gröger M, Loewe R, Kohrgruber N, Schrögendorfer KF, Prager G, Beck H, Pospisilik JA, Zeyda M, Stulnig TM, Patsch W, Wagner O, Esterbauer H, Bilban M.
Cell Metab. 2013 Jul 2; 18(1):62-74 PMID:23823477

Oncostatin M is a FIP1L1/PDGFRA-dependent mediator of cytokine production in chronic eosinophilic leukemia. 
Hoermann G, Cerny-Reiterer S, Sadovnik I, Müllauer L, Bilban M, Gröger M, Horny HP, Reiter A, Schmitt-Graeff A, Mannhalter C, Valent P, Mayerhofer
M.Allergy. 2013 Jun;68(6):713-23. doi: 10.1111/all.12139. Epub 2013 Apr 27. PMID:23621172

Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature. 
Demyanets S, Kaun C, Pentz R, Krychtiuk KA, Rauscher S, Pfaffenberger S, Zuckermann A, Aliabadi A, Gröger M, Maurer G, Huber K, Wojta J.
J Mol Cell Cardiol. 2013 Apr 6; 60C:16-26. doi: 10.1016/j.yjmcc.2013.03.020. [Epub ahead of print] PMID:23567618

Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling. 
Lang M, Borgmann M, Oberhuber G, Evstatiev R, Jimenez K, Dammann KW, Jambrich M, Khare V, Campregher C, Ristl R, Gasche C.
Mol Cancer. 2013 May 13;12(1):41. doi: 10.1186/1476-4598-12-41. PMID:23668310

Epidermal growth factor facilitates melanoma lymph node metastasis by influencing tumor lymphangiogenesis. 
Bracher A, Cardona AS, Tauber S, Fink AM, Steiner A, Pehamberger H, Niederleithner H, Petzelbauer P, Gröger M, Loewe R.
J Invest Dermatol. 2013 Jan;133(1):230-8. doi: 10.1038/jid.2012.272. Epub 2012 Sep 6. PMID:22951723

Macrophage-derived interleukin-33 is a critical factor for placental growth.
Fock V., Mairhofer M., Otti G.R., Spittler A., Zeisler H., Fiala C., Knöfler M., and J. Pollheimer.
Journal of Immunology 2013, 191:3734-43.

Preterm neonates display altered plasmacytoid dendritic cell function and morphology.
Schüller SS, Sadeghi K, Wisgrill L, Dangl A, Diesner SC, Prusa AR, Klebermasz-Schrehof K, Greber-Platzer S, Neumüller J, Helmer H, Husslein P, Pollak A, Spittler A, Förster-Waldl E. 
J Leukoc Biol. 2013, 93:781-8. PMID: 2341600

A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection.
Tiringer K, Treis A, Fucik P, Gona M, Gruber S, Renner S, Dehlink E, Nachbaur E, Horak F, Jaksch P, Döring G, Crameri R, Jung A, Rochat MK, Hörmann M, Spittler A, Klepetko W, Akdis CA, Szépfalusi Z, Frischer T, Eiwegger T.
Am J Respir Crit Care Med. 2013, 187:621-9. PMID: 23306544 
 

Acknowledgements

Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.

Gebeshuber CA, Kornauth C, Dong L, Sierig R, Seibler J, Reiss M, Tauber S, Bilban M, Wang S, Kain R, Böhmig GA, Moeller MJ, Gröne HJ, Englert C, Martinez J, Kerjaschki D.  
Nat Med. 2013, 19:481-7. PMID: 23502960


Proteome signatures of inflammatory activated primary human peripheral blood mononuclear cells.
Haudek-Prinz VJ, Klepeisz P, Slany A, Griss J, Meshcheryakova A, Paulitschke V, Mitulovic G, Stöckl J, Gerner C.
J Proteomics. 2012 Dec 5;76 Spec No.:150-62. doi: 10.1016/j.jprot.2012.07.012. Epub 2012 Jul 16.
PMID:22813876 | PMCID:PMC3509337

Proteome signatures of inflammatory activated primary human peripheral blood mononuclear cells.
Haudek-Prinz VJ, Klepeisz P, Slany A, Griss J, Meshcheryakova A, Paulitschke V, Mitulovic G, Stöckl J, Gerner C.J Proteomics. 2012 Dec 5;76 Spec No.:150-62. doi: 10.1016/j.jprot.2012.07.012. Epub 2012 Jul 16.
PMID: 22813876

MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.
Campregher C, Schmid G, Ferk F, Knasmüller S, Khare V, Kortüm B, Dammann K, Lang M, Scharl T, Spittler A, Roig AI, Shay JW, Gerner C, Gasche C.
PLoS One. 2012, 7(11):e50541. PMID:23209772

Cord blood derived CD4+ CD25(high) cells become functional regulatory T cells upon antigen encounter.
Mayer E, Bannert C, Gruber S, Klunker S, Spittler A, Akdis CA, Szépfalusi Z, Eiwegger T. 
PLoS One. 2012;7(1):e29355. PMID: 22272233

Clinical outcome of critically ill patients cannot be defined by cutoff values of monocyte human leukocyte antigen-DR expression.
Trimmel H, Luschin U, Köhrer K, Anzur C, Vevera D, Spittler A.
Shock. 2012, 37:140-4. PMID: 22089188 

 

 

Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques. 
Demyanets S, Konya V, Kastl SP, Kaun C, Rauscher S, Niessner A, Pentz R, Pfaffenberger S, Rychli K, Lemberger CE, de Martin R, Heinemann A, Huk I, Gröger M, Maurer G, Huber K, Wojta J.
Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2080-9. doi: 10.1161/ATVBAHA.111.231431. Epub 2011 Jul 7. PMID:21737781

Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial. 
Schlager O, Giurgea A, Schuhfried O, Seidinger D, Hammer A, Gröger M, Fialka-Moser V, Gschwandtner M, Koppensteiner R, Steiner S.
Atherosclerosis. 2011 Jul;217(1):240-8. doi: 10.1016/j.atherosclerosis.2011.03.018. Epub 2011 Apr 8. PMID:21481871

Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis. 
Hoermann G, Cerny-Reiterer S, Perné A, Klauser M, Hoetzenecker K, Klein K, Müllauer L, Gröger M, Nijman SM, Klepetko W, Valent P, Mayerhofer M.
Am J Pathol. 2011 May;178(5):2344-56. doi: 10.1016/j.ajpath.2011.01.020. Epub 2011 Mar 31. PMID:21457934 

 

 

 

 

Peptide orientation affects selectivity in ion-exchange chromatography.
Alpert AJ, Petritis K, Kangas L, Smith RD, Mechtler K, Mitulovic G, Mohammed S, Heck AJ.
Anal Chem. 2010 Jun 15;82(12):5253-9. doi: 10.1021/ac100651k.
PMID:20481592 | PMCID:PMC2884984

A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes.
Mazanek M, Roitinger E, Hudecz O, Hutchins JR, Hegemann B, Mitulovic G, Taus T, Stingl C, Peters JM, Mechtler K.J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 15;878(5-6):515-24. doi: 10.1016/j.jchromb.2009.12.017. Epub 2009 Dec 22. PMID: 20075017

 

 

 

 

A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes.
Mazanek M, Roitinger E, Hudecz O, Hutchins JR, Hegemann B, Mitulovic G, Taus T, Stingl C, Peters JM, Mechtler K.J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 15;878(5-6):515-24. doi: 10.1016/j.jchromb.2009.12.017. Epub 2009 Dec 22. PMID: 20075017

Preventing carryover of peptides and proteins in nano LC-MS separations.
Mitulovic G, Stingl C, Steinmacher I, Hudecz O, Hutchins JR, Peters JM, Mechtler K. Anal Chem. 2009 Jul 15;81(14):5955-60. doi: 10.1021/ac900696m. PMID: 19537771

 

 

 

 

HPLC techniques for proteomics analysis - a short overview of latest developments.
Mitulovic G, Mechtler K. Brief Funct Genomic Proteomic. 2006 Dec;5(4):249-60. Epub 2006 Nov 22. Review. PMID: 17124183

 

 

 

Effect of exercise on transdermal nicotine release in healthy habitual smokers.
Bur A, Joukhadar C, Klein N, Herkner, Mitulovic G, Schmid R, Agneter E, Müller M, Brunner M. Int J Clin Pharmacol Ther. 2005 May;43(5):239-43. PMID: 15906589

 

 

Automated, on-line two-dimensional nano liquid chromatography tandem mass spectrometry for rapid analysis of complex protein digests.
Mitulovic G, Stingl C, Smoluch M, Swart R, Chervet JP, Steinmacher I, Gerner C, Mechtler K. Proteomics. 2004 Sep;4(9):2545-57. PMID: 15352229

 

Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions.
Huber J, Vales A, Mitulovic G, Blumer M, Schmid R, Witztum JL, Binder BR, Leitinger N. Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):101-7. PMID: 11788468

Contribution of nicotine to acute endothelial dysfunction in long-term smokers.
Neunteufl T, Heher S, Kostner K, Mitulovic G, Lehr S, Khoschsorur G, Schmid RW, Maurer G, Stefenelli T.J Am Coll Cardiol. 2002 Jan 16;39(2):251-6. PMID: 11788216

An improved method for tracking and reducing the void volume in nano HPLC-MS with micro trapping columns.
Mitulovic G, Smoluch M, Chervet JP, Steinmacher I, Kungl A, Mechtler K. Anal Bioanal Chem. 2003 Aug;376(7):946-51. Epub 2003 Jul 11. PMID: 12856097